Recombinant activated factor VII for acute subdural haematoma in an elderly patient taking fondaparinux

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Recombinant activated factor VII for a patient with factor VII deficiency undergoing urgent intracerebral haematoma evacuation with underlying cavernous angioma.

Inherited factor VII (FVII) deficiency is a rare autosomal-recessive bleeding disorder. There are no clear guidelines regarding therapy in such patients when intracerebral surgery is performed. We report the use of recombinant activated FVII (rFVIIa) for the prophylaxis of bleeding in a female with FVII deficiency (8% of activity) undergoing urgent removal of a right fronto-rolandic intracerebr...

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Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage

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Spontaneous resolution of an acute subdural haematoma.

We report a case of a 47 year old man who presented with head injury due to road traffic accident, with CT scan suggestive of large left sided acute SDH with comminuted fracture of occipital bone. Within a few hours, patient showed significant neurological improvement. Follow-up CT scan revealed rapid spontaneous resolution and redistribution of the acute SDH. The proposed hypothesis explaining...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2008

ISSN: 0007-0912

DOI: 10.1093/bja/aen255